Dr. Nicolson’s Publications on Membrane Lipid Replacement

Dr. Nicolson’s Publications on Membrane Lipid Replacement with NTFactor Lipids®*

Prof. Emeritus Garth L. Nicolson, PhD, MD (H)

1. Nicolson GL. Chronic fatigue, aging, mitochondrial function and nutritional supplements. Townsend Letter 240(7): 72-76 (2003).
2. Ellithorpe RR, Settineri R. Nicolson GL. Reduction of fatigue by use of a dietary supplement containing glycophospholipids. J Am Nutraceut Assoc 2003; 6(1): 23-28. http://www.immed.org/illness/treatment_considerations.html
3. Agadjanyan M, Vasilevko V, Ghochikyan A, Berns P, Kesslak P, Settineri RA, Nicolson GL. Nutritional supplement (NT Factor) restores mitochondrial function and reduces moderately severe fatigue in aged subjects. J Chronic Fatigue Syndr 2003; 11(3): 23-36. http://www.immed.org/treatment considerations/06.16.12/AgadjanyanNicolsonJCFS.pdf
4. Nicolson GL. Lipid replacement as an adjunct therapy in chronic fatigue, anti-aging and restoration of mitochondrial function. J Am Nutraceut Assoc 2003; 6(3): 22-28. http://www.immed.org/treatment considerations/GNicolsonJANAvol6_3_.pdf
5. Nicolson GL. Lipid replacement/antioxidant therapy for anti-aging, fatigue and restoration of mitochondrial function. AgroFood High Tech 2004; 15(3): 20-23. http://agro-food-industry.teknoscienze.com/testata.asp?id_testata=36&folder=backissue
6. Nicolson GL. Lipid Replacement/Antioxidant Therapy as an adjunct supplement to reduce the adverse effects of cancer therapy and restore mitochondrial function. Pathol Oncol Res 2005; 11: 139-144.
   http://www.immed.org/publications/PORnicolson_copy.pdf
7. Nicolson GL, Ellithrope R. Lipid replacement and antioxidant nutritional therapy for restoring mitochondrial function and reducing fatigue in chronic fatigue syndrome and other fatiguing illnesses. J Chronic Fatigue Syndr 2006; 13(1): 57-68. http://www.immed.org/illness/treatment_considerations.html
8. Nicolson GL, Conklin KA. Molecular replacement for cancer metabolic and mitochondrial dysfunction, fatigue and the adverse effects of cancer therapy. Cancer Genomics Proteomics 2006; 3(3): 159-168. http://www.cgp-journal.com/pastissues/main.php?volume=3&issue=3-4
9. Nicolson GL. Metabolic syndrome and mitochondrial function: molecular replacement and antioxidant supplements to prevent membrane oxidation and restore mitochondrial function. J Cell Biochem 2007; 100(6): 1352-1369. DOI: 10.1002/jcb.21247 http://www.immed.org/fatigue_illness_research.html
10. Nicolson GL. Lipid replacement and antioxidant supplements to prevent membrane oxidation and restore mitochondrial function in metabolic syndrome and fatiguing illnesses. Townsend Lett 2007; 286: 112-120.
    http://www.townsendletter.com/May2007/lipidreplace0507_0709.html
11. Conklin KA, Nicolson GL. Molecular replacement in cancer therapy: reversing cancer metabolic and mitochondrial dysfunction, fatigue and the adverse effects of therapy. Curr Cancer Therapy Rev 2008; 4: 66-76.
    http://www.immed.org/JAN08Updates/NicolsonCCTR2.pdf
12. Nicolson GL, Conklin KA. Reversing mitochondrial dysfunction, fatigue and the adverse effects of chemotherapy of metastatic disease by Molecular Replacement Therapy. Clin Expl Metastasis 2008; 25: 161-169. http://www.springerlink.com/content/?k=pub%3a(Clinical+and+Experimental+Metastasis)+vol%3 a(25)&o=30
13. Nicolson GL, Ellithorpe R, Settineri R. Dietary supplement Healthy Curb for reducing weight, girth, body mass, appetite and fatigue while improving blood lipid values with NTFactor Lipid Replacement Therapy. J Invest Myalgic Encephalomyelitis 2009; 3(1): 39-48. http://www.immed.org/fatigue_illness_research.html
14. Nicolson GL. Finally an answer to the most common medical complaint—Fatigue. Public Health Alert 2011; (10): 1-5. http://www.immed.org/Fatigue Illness/10.01.11update/Nicolson Fatigue PHA2011.pdf
15. Nicolson GL. Lipid replacement therapy: a nutraceutical approach for reducing cancer-associated fatigue and the adverse effects of cancer therapy while restoring mitochondrial function. Cancer Metastasis Rev 2010; 29(3): 543-552.
    http://www.immed.org/cancer cell biology/CCB.update.8.8.2010/NicolsonC&MR2010.pdf
16. Nicolson GL, Ellithorpe RR, Ayson-Mitchell C, Jacques B, Settineri R. Lipid Replacement Therapy with a glycophospholipid-antioxidant-vitamin formulation significantly reduces fatigue within one week. J Am Nutraceutical Assoc 2010; 13(1): 10-14. http://www.ana-jana.org/reprints/JANA13-1Reprint-GarthNicolson.pdf
17. Nicolson GL. An answer to the most common medical complaint, fatigue. Explore 2011; 19: 1-4. http://www.immed.org/Fatigue Illness/10.01.11update/Nicolson Fatigue PHA2011.pdf
18. Nicolson GL, Settineri R. Lipid Replacement Therapy: a functional food approach with new formulations for reducing cellular oxidative damage, cancer-associated fatigue and the adverse effects of cancer therapy. Funct Food Health Dis 2011; 1(4): 135-160. http://www.functionalfoodscenter.net/files/49450894.pdf
19. Nicolson GL. Nutritional supplements, cancer-associated fatigue and cancer therapy—A molecular basis for restoring mitochondrial function. In Topics in Cancer Survivorship, vol 2, ISBN 978- 953-307-894-6, InTech, Rijeka, 147-164, 2011.
    http://cdn.intechopen.com/pdfs-wm/26741.pdf
20. Ellithorpe RA, Settineri R, Mitchell CA, Jacques B, Ellithorpe E, Nicolson GL. Lipid replacement therapy drink containing a glycophospholipid formulation rapidly and significantly reduces fatigue while improving energy and mental clarity. Funct Food Health Dis 2011; 1(8): 245-254. http://www.functionalfoodscenter.net/files/49450874.pdf
21. Ellithorpe RA, Settineri R, Jacques B, Nicolson GL. Lipid Replacement Therapy functional food with NT Factor for reducing weight, girth, body mass, appetite, cravings for foods and fatigue while improving blood lipid profiles. Funct Food Health Dis 2012; 2(1): 11-24. http://www.functionalfoodscenter.net/files/49450833.pdf
22. Nicolson GL, Settineri R, Ellithorpe E. Lipid Replacement Therapy with a glycophospholipid formulation with NADH and CoQ10 significantly reduces fatigue in intractable chronic fatiguing illnesses and chronic Lyme disease. Intern J Clin Med 2012; 3(3): 164-170. http://dx.doi.org/10.4236/ijcm.2012.33034
23. Nicolson GL, Settineri R, Ellithorpe E. Glycophospholipid formulation with NADH and CoQ10 significantly reduces intractable fatigue in chronic Lyme disease patients: preliminary report. Funct Food Health Dis 2012; 2(3): 35-47. http://www.functionalfoodscenter.net/files/50313126.pdf
24. Nicolson GL, Settineri R, Ellithorpe E. Lipid Replacement Therapy with a Glycophospholipid Formulation, NADH and CoQ10 Significantly Reduces Fatigue and Improves Mood and Cognition in Intractable Fatiguing Illnesses and Chronic Lyme Disease. Townsend Lett 2012; 347(6): 58-61. http://www.townsendletter.com/June2012/June2012.html
25. Nicolson GL. Mitochondrial dysfunction and disease: loss of mitochondrial function in chronic diseases and its reversal with Lipid Replacement Therapy. Public Health Alert 2012; (10): 1-4. http://www.publichealthalert.org/pdf/2012/2012_10.pdf
26. Ash M, Settineri R, Nicolson GL. Fatigue, Immunity and Inflammation: their resolution using natural medicine. Townsend Lett 2012; 352(10): 48-51. http://www.townsendletter.com/Nov2012/fatigue1112.html
27. Nicolson GL. Mitochondrial dysfunction and chronic disease: treatment with natural supplements. Alt Ther Health Med 2014; 20(Suppl 1): 18-25. http://www.immed.org/treatment%20considerations/05.23.14.Treatment%20Considerations/Mito_ Dysfunct_Treatm-NicolsonA THD2014.pdf
28. Nicolson GL, Ash ME. Lipid Replacement Therapy: a natural medicine approach to replacing damaged phospholipids in cellular membranes and organelles and restoring function. Biochim Biophys Acta 2014; 1838: 1657-1679. http://www.sciencedirect.com/science/journal/00052736/1838/6
29. Nicolson GL, Settineri R, Ellithorpe R. Neurodegenerative and fatiguing Illnesses, infections and mitochondrial dysfunction: use of natural supplements to restore mitochondrial function. Funct Foods Health Dis 2014; 4(1): 23-65.
    http://functionalfoodscenter.net/files/81861886.pdf
30. Nicolson GL. Mitochondrial dysfunction and chronic disease: treatment with natural supplements. Integr. Med. 2014; 13(4): 35-43.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566449/
31. Ellithorpe RR, Settineri R, Ellithorpe T, Nicolson GL. Blood homocysteine and fasting insulin levels are reduced and erythrocyte sedimentation rates are increased with a glycophospholipid- vitamin formulation: a retrospective study in older subjects. Funct Food Health Dis. 2015; 5(4): 126-135. http://functionalfoodscenter.net/files/102987419.pdf
32. Nicolson GL. Membrane Lipid Replacement: clinical studies using a natural medicine approach to restoring membrane function and improving health. Intern J Clin Med. 2016; 7: 133-143. http://www.scirp.org/Journal/PaperInformation.aspx?PaperID=63602
33. Nicolson GL, Rosenblatt S, Ferreira de Mattos G, Settineri R, Breeding PC, Ellithorpe RR, Ash ME. Clinical uses of Membrane Lipid Replacement supplements in restoring membrane function and reducing fatigue in chronic diseases and cancer. Discoveries, 2016; 4(1): e54. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941554/ or http://www.immed.org/treatment considerations/06.11.2016.update/Clinical_Uses_MLR- NicolsonDiscoveries2016.pdf
34. Nicolson GL, Ash ME. Membrane Lipid Replacement for chronic illnesses, aging and cancer using oral glycerolphospholipid formulations with fructooligosaccharides to restore phospholipid function in cellular membranes, organelles, cells and tissues. Biochim. Biophys. Acta Biomembranes 2017; 1859: 1704-1724. doi: org/10.1016/j.bbamem.2017.04.013 http://dx.doi.org/10.1016/j.bbamem.2017.04.013
35. Nicolson GL, Ferreira G, Settineri R, Ellithorpe RR, Breeding P, Ash ME. Mitochondrial dysfunction and chronic disease: treatment with Membrane Lipid Replacement and other natural supplements. In: Mitochondrial Biology and Experimental Therapeutics, (P. Oliveira, Ed.), Springer Press, New York, 499-522 (2018). https://doi.org/10.1007/978-3-319-73344-9_22
36. Ferreira G, Costa C, Bassaizteguy V, Santos M, Cardozo R, Montes J, Settineri R, Nicolson GL. Incubation of human sperm with micelles made from glycerolphospholipid mixtures increases sperm motility and resistance to oxidative stress. PloS One 2018; 13(6): article e0197897. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197897
37. Nicolson GL, Settineri R, Ferreira G, Breeding P. Reduction of pain, fatigue, gastrointestinal and other symptoms and improvement in quality of life indicators in fibromyalgia patients with Membrane Lipid Replacement glycerolphospholipids and controlled-release caffeine. Intern Journal of Clinical Medicine 2018; 9: 560-579. https://www.scirp.org/journal/paperinformation.aspx?paperid=86236
38. Gonzalez MJ, Seyfried T, Nicolson GL, Barclay BJ, Matta J, Vasquez A, Agostino DD, Olalde J, Duconge J, Hunninghake R, Berdiel MJ, Cintron A. Mitochondrial correction: a new therapeutic paradigm for cancer and degenerative diseases. J Orthomol Med. 2018; 33(4): 1-20. https://www.isom.ca/article/mitochondrial-correction-new-therapeutic-paradigm-cancer- degenerative-diseases/
39. Nicolson GL. Pathogenic mycoplasma infections in chronic illnesses: general considerations in selecting conventional and integrative treatments. Intern. J. Clin. Med. 2019; 10: 477-522. https://www.scirp.org/journal/paperinformation.aspx?paperid=95720
40. Nicolson GL, Ferriera de Mattos G. COVID-19 Coronavirus: Is infection along with Mycoplasma or other bacteria linked to progression to a lethal outcome? Intern. J. Clin. Med. 2020; 11: 282-302.
    https://www.scirp.org/journal/paperinformation.aspx?paperid=100307
41. Nicolson GL, Breeding PC. Membrane Lipid Replacement for reduction of pain, fatigue, gastrointestinal and other symptoms in patients with peripheral pain: case reports. Case Rep. Rev. 2020; 1(2): 1-3. https://www.sciencexcel.com/article/Membrane+Lipid+Replacement+for+reduction+of+pain,+fat igue,+gastrointestinal+and+other+symptoms+in+patients+with+peripheral+pain%3A+Case+reports
42. Nicolson GL, Breeding P. Membrane Lipid Replacement: reduction of pain, fatigue, gastrointestinal and other symptoms in patients with peripheral pain: case reports. J. Healthcare Prevent. 2020; 3(2): 1-4. https://www.omicsonline.org/open-access/membrane-lipid-replacement-for-reduction-of-pain- fatigue-gastrointestinal-and-other-symptoms-in-patients-with-peripheral.pdf
43. Nicolson GL, Breeding PC. Settineri R, Ferreira de Mattos G. Aging and chronic illnesses: Membrane Lipid Replacement for restoring mitochondrial function and reducing fatigue, pain, and other symptoms in aged individuals. Bioactive Comp. Health Dis. 2020; 3(10): 194-203. https://ffhdj.com/index.php/BioactiveCompounds/article/view/749/1339
44. Nicolson GL, Breeding PC. Membrane Lipid Replacement with NTFactor Lipids® reduces pain, fatigue, gastrointestinal and other symptoms in patients with peripheral pain. Townsend Lett. 2020; 449: 17-29.
45. Sfera A, Hazan S, Klein C, Zapata-Martin del Campo CM, Sasannia S, Anton JJ, Rahman L, Andronescu CV, Sfera DO, Kozakidis Z, Nicolson GL. Microbial translocation disorders: assigning an etiology to idiopathic illnesses. Applied Microbiology 2023; 3(1): 212-240.  https://www.mdpi.com/2673-8007/3/1/15

OTHER PUBLICATIONS ON MLR (not by Prof. Nicolson)

1. Colodny L, Lynch K, Farber C, Papish R, Phillips K, Sanchez M, Cooper K, Pickus O, Palmer D, Percy TB, Faroqui M, Block JB. Results of a study to evaluate the use of Propax to reduce adverse effects of chemotherapy. J Am Nutraceut Assoc. 2001; 3(1): 17-25.
2. Seidman MD, Khan MJ, Tang WX, Quirk WS. Influence of lecithin on mitochondrial DNA and age-related hearing loss. Otolaryngol Head Neck Surg. 2002; 127: 138-144.
3. Hirose A, Terauchi M, Osaka Y, Akiyoshi M, Kato K, Miyasaka N. Effect of soy lecithin on fatigue and menopausal symptoms in middle-aged women: a randomized, double-blind, placebo-controlled study. Nutrit. J. 2018; 17: article 4.
   doi: 10.1186/s12937-018-0314-5