Restoring energy and vitality...Naturally

Search Clinical Trials

The Date On Your Supplement Is Not An Expiration Date!

Learn More

NTFactor® Clinical Studies

Lipid Replacement Therapy Drink Significantly Reduces Fatigue

Glycophospholipid Formulation Rapidly and Significantly Reduces Fatigue While Improving Energy and Mental Clarity

Author: NTFactor®/Tuesday, October 16, 2012/Categories: Clinical Trials


Fatigue is the most common complaint of patients seeking general medical care and is often treated with stimulants. It is also important in various physical activities of relatively healthy men and women, such as sports performance.  Recent clinical trials using patients with chronic fatigue have shown the benefit of Lipid Replacement Therapy in restoring mitochondrial electron transport function and reducing moderate to severe chronic fatigue. 


Lipid Replacement Therapy was administered for the first time as an all-natural functional food drink (60 ml) containing polyunsaturated glycophospholipids but devoid of stimulants or herbs to reduce fatigue. This preliminary study used the Piper Fatigue Survey instrument as well as a supplemental questionnaire to assess the effects of the glycophospholipid 

drink on fatigue and the acceptability of the test drink in adult men and women.  A volunteer group of 29 subjects of mean age 56.2±4.5 years with various fatigue levels were randomly recruited in a clinical health fair setting to participate in an afternoon open label trial on the effects of the test drink. 


Using the Piper Fatigue instrument overall fatigue among participants was reduced within the 3-hour seminar by a mean of 39.6% (p<0.0001). All of the subcategories of fatigue showed significant reductions.  Some subjects responded within 15 minutes, and the majority responded within one hour with increased energy and activity and perceived improvements in 

cognitive function, mental clarity and focus. The test drink was determined to be quite acceptable in terms of taste and appearance.  There were no adverse events from the energy drink during the study.


The Lipid Replacement Therapy functional food drink appeared to be a safe, acceptable and potentially useful new method to reduce fatigue, sustain energy and improve perceptions of mental function.

Number of views (18213)/Comments (0)

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any pharmaceutical product without first consulting your prescribing physician.






Nutritional Therapeutics' reputation is closely linked to the purity, balance, and integrity of our products. For nearly three decades, NTI develops, manufactures, and distributes both OEM, and proprietary formulations of nutrition supplements for healthcare professional, and consumer markets throughout the world. We produce only natural products with scientifically formulated food ingredients, avoiding additives found in other dietary supplements and pharmaceutical products.

Copyright 2013 NT Factor / Nutritional Therapeutics     Terms Of Use    Privacy Statement